Intravenous Pentamidine for Pneumocystis Carinii/Jiroveci Pneumonia (PCP) Prophylaxis
نویسندگان
چکیده
منابع مشابه
Lobar pentamidine levels and Pneumocystis carinii pneumonia following aerosolized pentamidine.
Recent studies have suggested that failure of pentamidine prophylaxis against Pneumocystis carinii pneumonia (PCP) may be due to reduced deposition of pentamidine in the upper lobes. In this study, we performed bronchoalveolar lavage from the apical segment of the upper lobe and the middle lobe in 51 HIV-positive patients, all of whom were receiving prophylaxis with aerosolized pentamidine, who...
متن کاملPentamidine aerosol in prophylaxis and treatment of murine Pneumocystis carinii pneumonia.
The efficacy and tolerance of pentamidine aerosol were evaluated in the prophylaxis and therapy of murine Pneumocystis carinii pneumonia. P. carinii pneumonia was induced in rats by corticosteroid immunosuppression. Pentamidine was administered three times weekly via a Bird micronebulizer. The actual amount of pentamidine inhaled was estimated by monitoring the ventilation of the rats during th...
متن کاملRelapse of Pneumocystis carinii pneumonia in the upper lobes during aerosol pentamidine prophylaxis.
Pneumocystis carinii pneumonia was diagnosed by bronchoalveolar lavage of the upper lobes in a patient with the acquired immunodeficiency syndrome (AIDS) receiving aerosol pentamidine prophylaxis. Serendipitous availability of a normal premorbid lung gallium scan indicated that pneumocystosis had developed during aerosol pentamidine prophylaxis; at the time of presentation a repeat gallium scan...
متن کاملEffect of long-term primary aerosolized pentamidine prophylaxis on breakthrough Pneumocystis carinii pneumonia.
Aerosolized pentamide is a well-tolerated primary prophylaxis regimen for Pneumocystis carinii pneumonia (PCP) in human immunodeficiency virus (HIV)-infected patients. It is now commonly administered for prolonged periods. We therefore studied the effect of long-term inhalation on breakthrough PCP. We recorded clinical, immunological, radiological and microbiological data, as well as therapy an...
متن کاملPneumocystis hepatitis and choroiditis despite successful aerosolized pentamidine pulmonary prophylaxis.
A patient who developed Pneumocystis carinii hepatitis and choroiditis despite receiving prophylactic pentamidine therapy by aerosol is described. Liver biopsy showed histology typical of Pneumocystis hepatitis, but his respiratory status was stable and his lungs were free of P carinii organisms on BAL. Thus, inhaled pentamidine prophylaxis did not prevent extrapulmonary pneumocystosis. Patient...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2015
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2014.11.598